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Biochim Biophys Acta. 2006 Jan;1765(1):74-84. Epub 2005 Sep 8.

Identifying and defusing weapons of mass inflammation in carcinogenesis.

Author information

1
Department of Basic Pharmaceutical Sciences, College of Pharmacy, Coker Life Sciences, University of South Carolina, Columbia, SC 29208, USA. hofseth@cop.sc.edu

Abstract

The continued cancer risks associated with chronic inflammation necessitate the identification of inflammatory molecules and the cancer pathways they affect. Evidence indicates that there are multiple mechanisms linking inflammation to cancer and that there are multiple targets for chemoprevention. Here, we review some of the key factors and the cancer pathways they disturb as a necessary prerequisite to the identification of targets for chemoprevention.

PMID:
16169156
DOI:
10.1016/j.bbcan.2005.08.005
[Indexed for MEDLINE]

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