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Gynecol Oncol. 2005 Dec;99(3):770-3. Epub 2005 Sep 15.

Sarcoidosis mimicking recurrent endometrial cancer.

Author information

1
Department of Obstetrics, New Hanover Regional Medical Center, Coastal Area Health Education Center, 2131 South 17th Street, Wilmington, NC 28402-9025, USA. john.powell@coastalahec.org

Abstract

BACKGROUND:

Sarcoidosis is a multisystem disease and can be confused with benign or malignant tumors. In patients with recurrent gynecologic cancer, liver and intrathoracic lesions should undergo a biopsy to rule in metastatic malignancy, as clinical findings and CAT scan results may represent other disease processes.

CASE:

A 67 year old woman had a total abdominal hysterectomy, bilateral salpingo-oophorectomy, pelvic and periaortic lymphadenectomy, and peritoneal cytology in 2001 for Stage I B grade 1 adenocarcinoma of the endometrium. She developed a vaginal recurrence in 2005. A CT scan of lungs, abdomen, and pelvis revealed extensive mediastinal adenopathy and multiple space occupying hepatic lesions worrisome for metastatic disease. A needle biopsy of the largest liver lesion revealed sarcoidosis.

CONCLUSION:

Sarcoid lesions may mimic metastatic disease in patients with malignancy, potentially leading to delayed and/or inappropriate therapy.

PMID:
16168469
DOI:
10.1016/j.ygyno.2005.08.002
[Indexed for MEDLINE]

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