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Nat Rev Mol Cell Biol. 2005 Nov;6(11):885-91.

Innovation: Photoactivatable fluorescent proteins.

Author information

  • 1Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, Moscow 117997, Russia. kluk@ibch.ru

Abstract

The fluorescence characteristics of photoactivatable proteins can be controlled by irradiating them with light of a specific wavelength, intensity and duration. This provides unique possibilities for the optical labelling and tracking of living cells, organelles and intracellular molecules in a spatio-temporal manner. Here, we discuss the properties of the available photoactivatable fluorescent proteins and their potential applications.

PMID:
16167053
DOI:
10.1038/nrm1741
[PubMed - indexed for MEDLINE]
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