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Eur J Cancer. 2006 Jan;42(1):55-64. Epub 2005 Sep 12.

The development of the EORTC QLQ-C15-PAL: a shortened questionnaire for cancer patients in palliative care.

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Research Unit, Department of Palliative Medicine, Bispebjerg Hospital, 23, Bispebjerg Bakke, DK-2400 Copenhagen NV, Denmark.


This study aimed at developing a shortened version of the EORTC QLQ-C30, one of the most widely used health-related quality of life questionnaires in oncology, for palliative care research. The study included interviews with 41 patients and 66 health care professionals in palliative care to determine the appropriateness, relevance and importance of the various domains of the QLQ-C30. Item response theory methods were used to shorten scales. Patients and health care professionals rated pain, physical function, emotional function, fatigue, global health status/quality of life, nausea/vomiting, appetite, dyspnoea, constipation, and sleep as most important. Therefore, these scales/items were retained in the questionnaire. Four scales were shortened without reducing measurement precision. Important dimensions not covered by the questionnaire were identified. The resulting 15-item EORTC QLQ-C15-PAL is a 'core questionnaire' for palliative care. Depending on the research questions, it may be supplemented by additional items, modules or questionnaires.

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