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Neurocrit Care. 2005;2(2):179-82.

Intra-arterial thrombolysis of a distal internal carotid artery occlusion in an adolescent.

Author information

1
Department of Radiology, The Ohio State University College of Medicine, Columbus, OH 43210, USA. bourekas-1@medctr.osu.edu

Abstract

INTRODUCTION:

This article describes the first reported case of an adolescent being treated with intra-arterial urokinase for a distal internal carotid artery occlusion.

METHODS:

A 15-year-old male presenting with an acute ischemic stroke caused by a distal internal carotid artery occlusion was treated with intra-arterial urokinase at 5 hours and 45 minutes after symptom onset.

RESULTS:

The artery completely recanalized, and the patient improved significantly from an admission National Institutes of Health Stroke Scale (NIHSS) score of 28 to a NIHSS score of 8 at a 2.5-month follow-up, despite an asymptomatic intraparenchymal hemorrhage.

CONCLUSION:

This article reviews the only two reported cases of intravenous thrombolysis and three cases of intra-arterial thrombolysis in children with ischemic stroke and suggests that thrombolytic therapy should be considered a treatment option in selected pediatric patients with stroke, especially in adolescents who are generally treated as young adults.

PMID:
16159062
DOI:
10.1385/NCC:2:2:179
[Indexed for MEDLINE]
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