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Urologe A. 1992 May;31(3):182-5.

[Separation of urologic tumors cells from Cell Saver blood using a membrane filter. A new method in autotransfusion?].

[Article in German]

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Abteilung für Urologie, Klinikum der Universität, Heidelberg.


Tumor cells of three urological longterm cell lines have been labelled with 35[S]-Methionin and added to red cell concentrates. Red cell concentrates rich in tumor cells were passed through a cell saver and two special membranfilters under standard conditions. The 35[S]-Methionin labelled tumor cells were detected by liquid scintillation counting. On an average, only 0.027% of the radioactivity was left after passing through the cell saver and the membran filters in the 12 experiments. If investigations in clinical use of cell-saver and membran filter confirm these results, there will be significant consequences in urological tumor surgery by the possibility of transfusing the salvaged autologous blood.

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