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Trends Biotechnol. 2005 Nov;23(11):539-43. Epub 2005 Sep 12.

Metagenomics-based drug discovery and marine microbial diversity.

Author information

1
South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, China 510301. lixiang@scsio.ac.cn

Abstract

As the global threat of drug-resistant pathogens continues to rise, new strategies and resources are required to accelerate and advance the drug discovery process. We believe that rapid progress in metagenomics has opened up a new era in the study of marine microbial diversity that enables direct access to the genomes of numerous uncultivable microorganisms. This review outlines recent developments and future trends in metagenomics-based drug discovery in marine microbial communities and their associated chemical prosperity.

PMID:
16154653
DOI:
10.1016/j.tibtech.2005.08.006
[Indexed for MEDLINE]

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