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Structure. 2005 Sep;13(9):1239-40.

Evolution of NAD biosynthetic enzymes.

Author information

1
Department of Genetics, Dartmouth Medical School,Lebanon, NH 03756, USA.

Abstract

Two research groups have solved crystal structures of nicotinic acid phosphoribosyltransferase (PRTase) and made the argument that PRTases in three distinct pathways of nicotinamide adenine dinucleotide (NAD) biosynthesis evolved from a common ancestor (Shin et al., 2005 and Chappie et al., 2005).

PMID:
16154080
DOI:
10.1016/j.str.2005.08.004
[Indexed for MEDLINE]
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