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Gene. 2005 Nov 7;360(2):120-30. Epub 2005 Sep 8.

Congruence of evidence for a Methanopyrus-proximal root of life based on transfer RNA and aminoacyl-tRNA synthetase genes.

Author information

1
Department of Biochemistry and Applied Genomics Laboratory, Hong Kong University of Science and Technology, Hong Kong, PR China.

Abstract

Among 60 organisms, the intraspecies genetic distances between tRNAs cognate for different amino acids, between the initiator and elongator tRNAs for Met, and between potentially paralogous pairs of aminoacyl-tRNA synthetases are found to be at a minimum within the Methanopyrus kandleri genome. These results indicate an exact congruence between the evidence from tRNA and aminoacyl-tRNA synthetase genes locating the root of life closest to this organism.

PMID:
16153784
DOI:
10.1016/j.gene.2005.06.027
[Indexed for MEDLINE]

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