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Psychosomatics. 2005 Sep-Oct;46(5):392-401.

Ethical challenges in the care of persons with hepatitis C infection: a pilot study to enhance informed consent with veterans.

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Department of Psychiatry, University of New Mexico School of Medicine, NM, USA.


Psychiatric and addictive disorders are often considered contraindications to hepatitis C virus (HCV) treatment. In this pilot study, the ability of 30 veterans to provide informed consent for combined antiviral HCV therapy was examined with a mental health assessment protocol specifically geared to evaluate capacity in this area. The results showed that subjects lacked essential knowledge regarding the course of the disease and the nature of antiviral treatment despite receiving prior counseling. Informed consent assessments of candidates for HCV treatment may identify deficits that are responsive to intervention, thereby allowing patients with comorbid psychiatric and addictive disorders to receive effective HCV treatment.

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