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Rev Pneumol Clin. 2005 Jun;61(3):186-92.

[Pulmonary alveolar phospholipoproteinosis].

[Article in French]

Author information

1
Service de Pneumologie, Centre Cardio-Pneumologique, Hôpital Pontchaillou, CHU, 35033 Rennes Cedex. philippe.delaval@chu-rennes.fr

Abstract

Pulmonary alveolar phospholipoproteinosis is a rare lung disease of unknown cause characterized by surfactant plugging of the alveoli. At the present time, surgical lung biopsy, long considered as the gold standard, is not necessary for positive diagnosis of pulmonary alveolar phospholipoproteinosis when computed tomography anomalies and analysis of bronchial lavage fluids present a typical pattern. Treatment requires abundant lavage, but the demonstration of anti-GM-CSF antibodies in primary forms opens new therapeutic perspectives.

PMID:
16142192
[Indexed for MEDLINE]

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