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Nat Cell Biol. 2005 Sep;7(9):916-7.

Directionality of F-actin cables changes during the fission yeast cell cycle.

Author information

1
Division of Biology, Graduate School of Arts and Sciences, University of Tokyo, Tokyo, 153-8902, Japan.

Abstract

Longitudinal F-actin cables are thought to be important for transporting materials for polarized cell growth in fission yeast. We show that most F-actin in the cables is oriented such that the barbed end faces the nearest cell tip during interphase; however, this directionality is reversed during mitosis. These orientations of F-actin ensure proper transport of materials to growing sites during these cell-cycle stages.

PMID:
16136186
DOI:
10.1038/ncb1295
[Indexed for MEDLINE]

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