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Chromosome Res. 2005;13(5):431-41.

Drosophila telomeres: the non-telomerase alternative.

Author information

1
Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov St., Moscow 119334, Russia.

Abstract

In most eukaryotes, telomeres are composed of simple repetitive sequences renewable by telomerase. By contrast, Drosophila telomeres comprise arrays of non-LTR retrotransposons HeT-A, TART, and TAHRE belonging to three different families. However, closer inspection reveals that the two quite different telomere systems share quite a few components and regulatory circuits. Here we present the current knowledge on Drosophila telomeres and discuss the possible mechanisms of telomere length control.

PMID:
16132809
DOI:
10.1007/s10577-005-0992-7
[Indexed for MEDLINE]

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