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Biosci Biotechnol Biochem. 2005 Aug;69(8):1603-5.

A phytochemical in the edible Tamogi-take mushroom (Pleurotus cornucopiae), D-mannitol, inhibits ACE activity and lowers the blood pressure of spontaneously hypertensive rats.

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1
Three B Co., Inc., Nanporo, Japan.

Abstract

D-Mannitol, one of the main phytochemicals of the edible Tamogi-take mushroom (Pleurotus cornucopiae), was found to inhibit an angiotensin I converting enzyme (ACE). The antihypertensive effect of D-mannitol and a hot water extract of Tamogi-take mushroom was demonstrated in spontaneously hypertensive rats (SHR) by oral administration.

PMID:
16116292
DOI:
10.1271/bbb.69.1603
[Indexed for MEDLINE]
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