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Cytokine. 2005 Sep 21;31(6):415-8.

Urinary interleukin-8 is elevated in urinary tract infections independently of the causative germs.

Author information

1
Laboratoire de Bactériologie, CHU de Nice, France. oregioni.o@chu-nice.fr

Abstract

Interleukin-8 elevation in urine during urinary tract infections (UTIs) has been documented for different uropathogenic germs in 85 patients. We showed that for 17 different isolates, IL-8 was increased in 92% of UTIs with an average value of 627 pg/ml for infected, as compared to 45 pg/ml for uninfected patients. We suggest that the high negative predictive value of the IL-8 urine assay could be useful to eliminate UTIs in routine screenings.

PMID:
16115778
DOI:
10.1016/j.cyto.2005.06.009
[Indexed for MEDLINE]

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