Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Surg. 2005 Sep;190(3):474-8.

A systematic review of whether oral contrast is necessary for the computed tomography diagnosis of appendicitis in adults.

Author information

1
Department of Surgery, University of Washington, BB 431, Seattle, WA 98195, USA.

Abstract

BACKGROUND:

There are several methods of contrast administration when performing computed tomography (CT) scanning for suspected appendicitis. In this systematic review we evaluated the diagnostic performance of CT with and without contrast material.

METHODS:

Twenty-three reports were identified using a Medline search.

RESULTS:

The aggregated diagnostic performance characteristics of all modes of CT scanning were excellent with a range of sensitivity (83--97%), specificity (93--98%), positive predictive value (86--98%), negative predictive value (94--99%), and accuracy (92--97%). The diagnostic performance of CT without oral contrast was similar (sensitivity, 95% vs. 92% [not statistically significant]; negative predictive value, 96% for both protocols) or surprisingly better (specificity, 97% vs. 94%; positive predictive value, 97% vs. 89%; accuracy, 96% vs. 92%; P<.0001) than with oral contrast.

CONCLUSIONS:

Noncontrast CT techniques to diagnose appendicitis showed equivalent or better diagnostic performance compared with CT scanning with oral contrast. A prospective comparative trial of CT with and without oral contrast for appendicitis should be performed to assess the adequacy of this modality.

PMID:
16105539
DOI:
10.1016/j.amjsurg.2005.03.037
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center