Format

Send to

Choose Destination
Arch Dermatol Res. 1992;284(2):92-4.

Infrared radiation suppresses ultraviolet B-induced sunburn-cell formation.

Author information

1
Department of Dermatology, Kyoto University Faculty of Medicine, Japan.

Abstract

Sunburn cell (SC) formation, a quantifiable measure of epidermal cell injury induced in mouse ear skin by ultraviolet-B (UVB) radiation (290-320 nm), was significantly decreased by pre-exposure to infrared radiation (IR), which elevated the surface temperature of ear lobes to 37-42 degrees C. An autoradiographic study demonstrated that the basal cell labelling indices were significantly reduced in a surface temperature-dependent manner by pre-exposure to IR. Taken together with our previous findings that SC formation depends upon the ratio of cycling to non-cycling cells, the present findings suggest that IR retards the cell cycle and, as a result, decreases SC formation. SC counts were not altered by post-UVB exposure to IR. The effect of IR or the IR-induced increase in surface temperature should be considered when studying cutaneous damage by UVB and sunlight.

PMID:
1610218
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center