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Curr Opin Genet Dev. 2005 Oct;15(5):507-14.

Bacterial chromatin.

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1
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK. aat@mrc-lmb.cam.ac.uk

Abstract

Recent studies have revealed that the bacterial nucleoid is a dynamic entity that alters its overall structure in response to changes in both growth rate and growth phase. These structural changes are correlated with, and might be driven by, changes in the distribution and utilization of DNA supercoiling. In turn, these parameters in addition to the delimitation of topological domains are dependent both on the relative proportions of the abundant nucleoid-associated proteins and on transcriptional activity. The domain structure itself is dynamic.

PMID:
16099644
DOI:
10.1016/j.gde.2005.08.006
[Indexed for MEDLINE]
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