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Am J Obstet Gynecol. 2005 Aug;193(2):577-80; discussion 580-1.

Upper vaginectomy for the treatment of vaginal intraepithelial neoplasia.

Author information

1
Department of Gynecology Onclogy, University of South Florida, Tampa, FL, USA.

Abstract

OBJECTIVE:

The purpose of this study was to evaluate the use of upper vaginectomy for the treatment of vaginal intraepithelial neoplasia (VAIN).

STUDY DESIGN:

We conducted a retrospective review. Between August 1, 1985 and April 30, 2004, 105 patients were identified who had undergone upper vaginectomy for VAIN.

RESULTS:

Thirty-six patients had previously been treated for VAIN. Mean operative time and estimated blood loss were 55 minutes and 113 mL, respectively. Ten percent had intraoperative complications. Twenty-three (22%) patients had negative findings on final pathologic examination, and invasive cancer was found in 13 (12%) patients. Four patients had postoperative complications. Follow-up was available in 52 patients; 46 (88%) remain without recurrence at a mean follow-up of 25 months.

CONCLUSION:

In our patients, upper vaginectomy was efficacious for the treatment of VAIN. The procedure led to the diagnosis of occult invasive cancer in 12% of these women.

PMID:
16098901
DOI:
10.1016/j.ajog.2005.03.055
[Indexed for MEDLINE]

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