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Arch Virol. 2006 Jan;151(1):113-25. Epub 2005 Aug 12.

Dengue 2 genotypes in the state of Oaxaca, Mexico.

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Sección de Estudios de Postrado e Investigación de la Escuela Nacional de Medicina y Homeopatía del IPN, México.


To genetically characterize dengue 2 (DEN-2) viruses in Oaxaca, Mexico, the C protein, and a portion of the prM protein genes of 8 isolates from the 2001 DEN epidemic were sequenced. The sequences were compared to those of prototype DEN-2 viruses from various parts of the world. Phylogenetic analysis suggested that the 2001 isolates of DEN-2 were of the American/Asian genotype and were most similar to the Jamaica and Venezuelan isolates MARA3, LARD1996 and LARD1910. Molecular analyses confirmed the origin of the isolates. This study indicates that DEN-2 strains of American/Asian genotype probably from Southeast Asian are circulating in Oaxaca.

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