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Pediatr Emerg Care. 2005 Aug;21(8):546-8; quiz 549-51.

Myasthenia gravis: myasthenia vs. cholinergic crisis.

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Pediatric Department, Medical University of South Carolina, Charleston, SC 29425, USA.


A serious complication of myasthenia gravis is respiratory failure. This may be secondary to an exacerbation of myasthenia (myasthenia crisis) or to treatment with excess doses of a cholinesterase inhibitor (cholinergic crisis). Managing respiratory failure and differentiating a myasthenia from a cholinergic crisis is reviewed. Due to the unpredictable development of respiratory failure, hospitalization is recommended for most patients with exacerbations or complications of myasthenia gravis.

[Indexed for MEDLINE]

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