Format

Send to

Choose Destination
Infect Control Hosp Epidemiol. 2005 Jul;26(7):654-7.

Risk factors for nosocomial infective endocarditis in patients with methicillin-resistant Staphylococcus aureus bacteremia.

Author information

1
Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China. ronbin@ha.mc.ntu.edu.tw

Abstract

BACKGROUND AND OBJECTIVE:

Nosocomial infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are increasing. Only a few studies of MRSA infective endocarditis have been conducted, and none have reported its risk factors. We sought to determine the host-related risk factors for infective endocarditis in patients with nosocomial MRSA bacteremia.

SETTING:

A 2,000-bed, university-affiliated, tertiary-care hospital.

PATIENTS:

Thirty-one patients with nosocomial MRSA infective endocarditis between October 1996 and May 2003.

DESIGN:

A retrospective chart review was conducted. Data were compared with those from a control group of patients with nosocomial MRSA bacteremia. Logistic regression was used to identify independent risk factors for nosocomial infective endocarditis.

RESULTS:

Compared with patients who had nosocomial MRSA bacteremia and no infective endocarditis, patients who had infective endocarditis had a higher incidence of chronic liver disease and a lower incidence of immunodeficiency. The risk of developing infective endocarditis was approximately 10% for patients with nosocomial MRSA bacteremia.

CONCLUSION:

Patients with MRSA bacteremia and underlying chronic liver disease were prone to infective endocarditis.

PMID:
16092748
DOI:
10.1086/502597
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Cambridge University Press
Loading ...
Support Center