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Nature. 1992 Jun 18;357(6379):563-9.

Gustducin is a taste-cell-specific G protein closely related to the transducins.

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1
Roche Institute of Molecular Biology, Roche Research Center, Nutley, New Jersey 07110-1199.

Abstract

A novel G protein alpha-subunit (alpha-gustducin) has been identified and cloned from taste tissue. alpha-Gustducin messenger RNA is expressed in taste buds of all taste papillae (circumvallate, foliate and fungiform); it is not expressed in non-sensory portions of the tongue, nor is it expressed in the other tissues examined. alpha-Gustducin most closely resembles the transducins (the rod and cone photoreceptor G proteins), suggesting that gustducin's role in taste transduction is analogous to that of transducin in light transduction.

PMID:
1608467
DOI:
10.1038/357563a0
[Indexed for MEDLINE]
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