Format

Send to

Choose Destination
Arch Environ Health. 2004 Feb;59(2):101-8.

Odor from industrial hog farming operations and mucosal immune function in neighbors.

Author information

1
Department of Epidemiology, School of Public Health, University of North Carolina Chapel Hill, North Carolina 27599-7435, USA. ravery@email.unc.edu

Abstract

The authors evaluated whether exposure to malodor from industrial hog farming operations has a psychophysiologically mediated immunosuppressive effect on secretory immunoglobulin A (sIgA) in neighbors. Fifteen adults living within 2.4 km (1.5 mi) of at least one hog farming operation rated odor intensity on a 9-point scale and provided saliva samples twice daily for two weeks. The authors used hierarchical regression to model the association between reported odor and sIgA; study participants were their own controls. The natural log of slgA concentration and secretion rate declined, on average, 0.058 (0.032) and 0.116 (0.103), respectively, for each incremental 1-unit increase in reported odor from 4 to 9, adjusted for time of day, suggesting reduced levels of sIgA in response to moderate or high odor. Findings support the hypothesized immunosuppressive effect of malodor on mucosal immunity and provide preliminary data useful in understanding health effects related to malodor from industrial hog farming operations.

PMID:
16075904
DOI:
10.3200/AEOH.59.2.101-108
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center