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Int J Oral Maxillofac Surg. 2005 Jul;34(5):576-8.

Response of diffuse sclerosing osteomyelitis of the mandible to alendronate: follow-up study by 99mTc scintigraphy.

Author information

1
Department of Oral and Maxillofacial Surgery, Ehime University School of Medicine, Ehime, Japan. sahino@m.ehime-u.ac.jp

Abstract

We report a case of diffuse sclerosing osteomyelitis of the mandible responded to alendronate, after a poor response to intravenous antibiotics, antibiotic irrigation-perfusion, and decortication. The patient was given an intravenous infusion of 10mg of alendronate. Pain resolved within 24 h. There were no severe adverse events. Increased uptake of 99mTc in the mandible almost completely disappeared 3 months after treatment.

PMID:
16053881
DOI:
10.1016/j.ijom.2005.01.003
[Indexed for MEDLINE]

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