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Ophthal Plast Reconstr Surg. 2005 Jul;21(4):321-2.

Bowen disease of the eyelid successfully treated with imiquimod.

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  • 1University of Cincinnati, Department of Ophthalmology, Cincinnati Eye Institute, Ohio 45242, USA.


We present a case of Bowen disease affecting the eyelid that was successfully treated with imiquimod. The clinical presentation, histopathology, and treatment of this case are presented. The tumor was treated with imiquimod for 3 months, leading to complete resolution of the disease both clinically and histopathologically. There was no evidence of recurrence 5 months after treatment cessation. Imiquimod was safely used on the eyelid in this case and may avoid extensive periocular tumor excision and reconstruction in Bowen disease.

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