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Clin Exp Dermatol. 2005 Sep;30(5):471-3.

Itching for progress.

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1
Dermatology, University of Edinburgh, Edinburgh, UK. johnathan.rees@ed.ac.uk

Abstract

The study of itch remains a neglected field, with a number of barriers limiting satisfactory therapy in the majority of instances. We review recent advances, focusing on the identification of the neural pathways, distinct from pain, that signal itch; methods to measure itch as scratch in humans; and the identification of a role for H4 receptors in mediating itch (in the mouse).

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