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Phytother Res. 2005 Apr;19(4):346-8.

Stimulation of lymphocyte proliferation and inhibition of nitric oxide production by aqueous Urtica dioica extract.

Author information

1
Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey.

Abstract

The immunomodulatory and antiinflammatory activities of aqueous Urtica dioica extract were investigated for their effect on the mitogenic response of murine splenocytes and nitric oxide production by murine peritoneal macrophages in vitro. It was found that this extract stimulated the proliferation of T-lymphocytes and suppressed NO production in lipopolysaccharide-stimulated macrophages without affecting cell viability.

PMID:
16041733
DOI:
10.1002/ptr.1686
[Indexed for MEDLINE]

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