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Int J Toxicol. 2005 May-Jun;24(3):165-71.

Determination of lead in Smilax luzonensis herbal preparations in Malaysia.

Author information

1
School of Pharmaceutical Sciences, University Science Malaysia, Minden, Penang, Malaysia. hhang@usm.my

Abstract

The DCA (Drug Control Authority) of Malaysia implemented the phase 3 registration of traditional medicines on 1 January 1992. As such, a total of 100 products in various pharmaceutical dosage forms of a herbal preparation containing Smilax luzonensis, either single or combined preparations, were analyzed for the presence of lead, using atomic absorption spectrophotometry. Results showed that 14% of the above products possessed 10.02 to 21.21 ppm of lead, and, therefore, they failed to comply with the quality requirement for traditional medicines in Malaysia ( <10 ppm). Although this study showed that 86% of the products complied with the quality requirement for traditional medicines in Malaysia pertaining to lead, they cannot be assumed safe from lead contamination because of batch-to-batch inconsistency.

PMID:
16040569
DOI:
10.1080/10915810590952942
[Indexed for MEDLINE]

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