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Ophthalmic Epidemiol. 2005 Jun;12(3):215-9.

Post-cycloplegia myopic shift in an older population.

Author information

1
The Eye Hospital, Launceston, Australia.

Abstract

PURPOSE:

To demonstrate that use of a mydriatic agent remains a significant confounder in autorefraction of the presbyopic population.

METHODS:

The pre- and post-cycloplegic autorefraction results of 37 subjects over 50 years of age were measured using a Humphrey-598 autorefractor. The results of both eyes were included in a multivariate regression analysis.

RESULTS:

The average age of the patient sample was 63.4 years. The mean spherical equivalent (SEQ) shifts for the hyperopic, myopic, pseudophakic, and emmetropic eyes were -0.53 D (95% CI -0.77 D to -0.39 D; p < 0.001), -0.38 D (95%CI -0.81 D to +0.04 D; p = 0.077), -0.49 D (95% CI -0.78 D to -0.20 D; p = 0.001), and -0.35 D (95% CI -0.59 D to -0.11 D; p = 0.004), respectively.

CONCLUSION:

Cyclopleged autorefraction in the presbyopic population is associated with a myopic shift that can potentially lead to overestimation of myopic prevalence. This is an important factor in comparing population studies where cyclogleged autorefraction is used in contrast to non-cyclopleged autorefraction and subjective refraction.

PMID:
16036481
DOI:
10.1080/09286580590964784
[Indexed for MEDLINE]

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