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Dermatol Surg. 2005 Jul;31(7 Pt 2):886-9; discussion 889.

Review of skin-lightening agents.

Author information

1
Department of Dermatology, Dermatology and Aesthetic Center, Boca Raton, Florida 33486, USA. jimibrain@yahoo.com

Abstract

BACKGROUND:

Multiple agents are available for the treatment of hyperpigmentation, a cosmetically important condition seen most often in middle-aged and elderly individuals and resulting from exposure to ultraviolet light, certain drugs or chemicals, or the existence of disease. Many skin-lightening agents cause skin irritation and require months of use before results appear, and some agents are only partly effective.

OBJECTIVE:

To help dermatologists make an informed decision when choosing a depigmenting agent.

METHODS:

A review of all depigmenting agents used alone and in combination, including its natural properties and information about safety, efficacy, and optimal dosing.

CONCLUSIONS:

The speed of efficacy and type and extent of side effects vary greatly among depigmenting agents. Knowing the properties associated with each agent enables a physician to choose a product that will best meet a patient's expectations and minimize adverse reactions.

PMID:
16029683
[Indexed for MEDLINE]

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