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Paediatr Anaesth. 2005 Aug;15(8):703-5.

Acute psychosis after anesthesia: the case for antibiomania.

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  • 1Northwestern University's Feinberg School of Medicine, Chicago, IL 60614, USA.


We report the case of a teenager who developed a postanesthesia acute psychosis (delusions, paranoia, and hallucinations) caused by a reaction to antibiotic therapy (amoxicillin and clarithromycin), so called 'Hoigne's syndrome' or 'antibiomania.' The differential diagnosis and a review of literature are presented. Our patient illustrates the importance of adding antibiomania as part of the differential diagnosis when altered postanesthesia behavior is observed in pediatric patients.

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