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J Neurol. 2006 Jan;253(1):33-7. Epub 2005 Jul 18.

Long-term survival of Parkinson's disease: a population-based study.

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Dipartimento di Neurologia, Oftalmologia Otorinolaringoiatria e Psichiatria, Università Degli Studi di Palermo, Via Gaetano La Loggia 1, 90129, Palermo, Italy.


In a set of a population- based study, long-term survival of 59 prevalent PD patients was compared with that of individuals free of neurological diseases matched 1:2 by sex and age of enrolment. PD individuals, compared with reference subjects, showed a two-fold increased risk of death (OR 2.1; 95 % CI 1.4, 3.1). Among causes of death, pneumonia and cachexia were significantly more frequent among PD patients than among individuals free of neurological diseases. We confirmed in a long-term follow-up study an increased mortality among PD individuals compared with that of the general population.

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