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J Oral Pathol Med. 2005 Aug;34(7):423-5.

Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy.

Author information

1
Stomatology Clinic, II University of Medicines and Surgery, Naples, Italy. femiano@libero.it

Abstract

BACKGROUND:

The objective of this study was to investigate the effect of zinc on recurrent herpes labialis.

MATERIALS/METHODS:

Twenty patients (12 females; median age 26.6 years) with a history of recurrent herpes labialis >6 episodes each year were treated with systemic zinc sulphate 22.5 mg twice daily for the months of February, March, September and October. All patients were followed for 12 months.

RESULTS:

Herpetic lesions reduced to <4 episodes (average 3) for the 12 months and the duration was <7 days for each episode (average 5.7).

CONCLUSIONS:

Systemic zinc sulphate appeared to reduce both the number of episodes and the time to recovery of herpes labialis.

[Indexed for MEDLINE]

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