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FEMS Microbiol Lett. 2005 Aug 15;249(2):207-9.

Moraxella catarrhalis is only a weak activator of the mannose-binding lectin (MBL) pathway of complement activation.

Author information

1
Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands. j.hays@erasmusmc.nl

Abstract

A hemolytic bystander assay was used to assess the functional serum mannose-binding lectin (MBL) activating capacity of five isolates of Moraxella catarrhalis obtained from children who suffered recurrent acute otitis media episodes. Results showed that this organism is only a poor activator of the lectin pathway of complement activation, with subsequent consequences for the etiology of otitis media by this organism.

PMID:
16006058
DOI:
10.1016/j.femsle.2005.05.048
[Indexed for MEDLINE]
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