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J Hepatol. 2005 Sep;43(3):508-14.

Prevalence of and risk factors for fatty liver in a general population of Shanghai, China.

Author information

1
Center for Fatty Liver, Shanghai First People's Hospital, JiaoTong University, Shanghai, China. fattyliver2004@hotmail.com

Abstract

BACKGROUND/AIMS:

To determine the prevalence and risk factors of fatty liver (FL) among Shanghai adults.

METHODS:

A cross-sectional ultrasonographic survey with randomized multistage stratified cluster sampling was used.

RESULTS:

The study included 3175 subjects (1218 men) with a mean age of 52 years. FL was found in 661 (20.82%) subjects. After adjustment by age and sex, FL prevalence was found to be 17.29%, and the prevalences of alcoholic, suspected alcoholic and nonalcoholic FL were determined to be 0.79, 1.15 and 15.35%, respectively. Generally, age, body mass index (BMI), waist circumference, blood pressure, and the prevalences of obesity, diabetes, hypertension and dyslipidemia were all significantly higher in FL patients than in controls; In contrast, the levels of high-density-lipoprotein cholesterol (HDL-C), education and physical activity were markedly lower. Multiple regression analyses showed that only nine factors (male, educational level, waist circumference, BMI, HDL-C, triglyceride, fasting plasma glucose, diabetes and hypertension) were closely related to FL. In excessive drinkers, obesity increased the risk for FL by 4.8-fold, but excessive drinking was associated with only a 1.5-fold increased risk in obese subjects.

CONCLUSIONS:

FL in Shanghai is highly prevalent and mainly related to multiple metabolic disorders.

PMID:
16006003
DOI:
10.1016/j.jhep.2005.02.042
[Indexed for MEDLINE]
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