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Arthritis Rheum. 1992 Jun;35(6):682-7.

Yersinia-triggered reactive arthritis. Use of polymerase chain reaction and immunocytochemical staining in the detection of bacterial components from synovial specimens.

Author information

1
Department of Medical Microbiology, Turku University, Finland.

Abstract

OBJECTIVE:

To investigate whether microbial DNA is present in synovial specimens from patients with Yersinia-triggered reactive arthritis.

METHODS:

Synovial specimens from 13 patients with Yersinia enterocolitica O:3-triggered reactive arthritis and from 16 control patients were studied using polymerase chain reaction and immunocytochemical staining techniques.

RESULTS:

Yersinia chromosomal DNA was not found in any of the synovial specimens from Yersinia-triggered arthritis patients or controls, whereas with immunocytochemical techniques, Yersinia antigens were observed in synovial specimens from all of the patients with Yersinia-triggered reactive arthritis.

CONCLUSION:

Only stable bacterial degradation products, not whole bacteria, are present at the site of inflammation in Yersinia-triggered reactive arthritis.

PMID:
1599522
DOI:
10.1002/art.1780350613
[Indexed for MEDLINE]

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