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Chemphyschem. 2005 Jul 11;6(7):1206-20.

Single-molecule fluorescence spectroscopy of protein folding.

Author information

1
Department of Biochemistry, University of Zürich, Winterthurerstr. 190, 8057 Zürich, Switzerland. schuler@bioc.unizh.ch

Abstract

Single-molecule spectroscopy is an important new approach for studying the intrinsically heterogeneous process of protein folding. This Review illustrates how different single-molecule fluorescence techniques have improved our understanding of mechanistic aspects in protein folding, exemplified by a series of recent experiments on a small protein.

PMID:
15991265
DOI:
10.1002/cphc.200400609
[Indexed for MEDLINE]

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