Send to

Choose Destination
Parasitol Res. 2005 Oct;97(3):255-7. Epub 2005 Jul 1.

Entamoeba histolytica and Entamoeba dispar infections in cynomolgus monkeys imported into Japan for research.

Author information

The Corporation for Production and Research of Laboratory Primates, 1 Hachimandai, Tsukuba-shi Ibaraki, 305-0843, Japan.


Three hundred and three stool samples of cynomolgus monkeys (Macaca fascicularis) imported from China and the Philippines were examined for Entamoeba histolytica/Entamoeba dispar infections. Microscopy detected E. histolytica/E. dispar cysts in 41 samples. Positive rates were higher in the monkeys from China (37.5%) than in the monkeys from the Philippines (3.7%). PCR analysis of 25 samples successfully cultured from the cysts demonstrated that 24 were E. dispar, one of the samples from China was E. histolytica. The one sample was also identified as E. histolytica by an antigen detection kit, although the monkey was asymptomatic and serology was negative. To our knowledge, this is the first report of E. histolytica isolation from cynomolgus monkeys based on the discrimination between E. histolytica and E. dispar.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center