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Gastrointest Endosc. 2005 Jul;62(1):55-61.

The value of wireless capsule endoscopy in patients with complicated celiac disease.

Author information

1
Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, NY, USA.

Abstract

BACKGROUND:

Celiac disease may be complicated by symptoms that raise the suspicion of small-intestinal malignancy. The objective is to evaluate wireless capsule endoscopy (WCE) in complicated celiac disease.

METHODS:

This is a prospective study at a university referral center. There were 47 patients. The indications for WCE were abdominal pain (57%), cancer surveillance (23%), blood in the stool, or persistent iron deficiency (19%).

RESULTS:

Findings were consistent with celiac disease in 87%: atrophy (68%), fissuring (62%), and mosaic pattern (19%), extending to the ileum in 34%. Unexpected findings were ulceration in 45% (n = 21), cancer (1), polyps (1), stricture (1), submucosal mass (1), ulcerated nodular mucosa (2), and intussusception (1) were seen in 60%.

CONCLUSIONS:

WCE has a high yield in complicated celiac disease, by identifying mucosal abnormalities and by excluding adenocarcinoma.

PMID:
15990820
[Indexed for MEDLINE]

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