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Neurosurg Clin N Am. 2005 Jul;16(3):517-40, vi.

Antiplatelet therapy in neuroendovascular therapeutics.

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Cleveland Clinic Foundation, 9500 Euclid Avenue, S80, Cleveland, OH 44195, USA.


Our understanding of the pharmacology of antiplatelet therapy continues to evolve rapidly. Although the existing data are primarily generated in the setting of interventional and preventative cardiology studies, these data may be extrapolated to guide the rational application of these agents in neuroendovascular procedures. Platelet function testing represents an increasingly available and practical method by which to verify the adequacy of therapy and guide clinical decision making. The optimal application of these agents will undoubtedly improve the risk profile of neuroendovascular procedures, increase the success rate of acute stroke intervention, and facilitate more effective secondary stroke prevention.

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