Format

Send to

Choose Destination
Antimicrob Agents Chemother. 2005 Jul;49(7):3009-10.

Compound efflux in Helicobacter pylori.

Author information

1
Infection Discovery, Cancer and Infection Research Area, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA.

Abstract

Susceptibility testing with a variety of structurally unrelated compounds showed that hefC in Helicobacter pylori is involved in multidrug efflux. This efflux was shown to depend on the proton motive force, as demonstrated by ethidium bromide accumulation experiments. Thus, H. pylori contains an active multidrug efflux mechanism.

PMID:
15980386
PMCID:
PMC1168643
DOI:
10.1128/AAC.49.7.3009-3010.2005
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center