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Eur J Radiol. 2005 Dec;56(3):370-5. Epub 2005 Jun 22.

Evaluation of quantitative CT indexes in idiopathic interstitial pneumonitis using a low-dose technique.

Author information

1
Department of Clinical Sciences, Section of Radiology, University of Parma, Via Rasori, 10 43100 Parma, Italy. nicolasve@tiscali.it

Abstract

OBJECTIVE:

To evaluate and compare histogram features (mean lung attenuation, skewness, kurtosis) of low-dose and standard-dose CT in a group of patients affected by idiopathic interstitial pneumonitis.

METHODS:

We analyzed 16 patients affected by idiopathic interstitial pneumonitis. Spiral whole lung thin-section CT acquisition at standard dose (100 mAs) and three additional low-dose (50 mAs) CT images were obtained. After obtained frequency histograms, mean lung attenuation (MLA), skewness and kurtosis and three range of density (-700/-200 HU; -700/-400 HU; -500/-200 HU) of the standard-and low-dose thin-section CT scans were analyzed and compared.

RESULTS:

The parameters obtained with low-dose and standard-dose spiral CT were correlated in a highly significant manner and were equivalent (p<0.01). The greatest correlation was found between standard-and low-dose kurtosis and standard and low-dose -700/-400 HU subrange of density (r=0.92; p<0.0001).

CONCLUSIONS:

Our results prove that a quantitative CT objective evaluation in lung fibrosis can be successfully obtained with low-dose spiral CT, with reduced mA.

PMID:
15978764
DOI:
10.1016/j.ejrad.2005.05.012
[Indexed for MEDLINE]

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