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Invest Radiol. 2005 Jul;40(7):412-20.

Magnetic resonance elastography of the breast: correlation of signal intensity data with viscoelastic properties.

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1
Department of Radiology, University Tuebingen, Tuebingen, Germany. tanja.xydeas@med.uni-tuebingen.de

Abstract

OBJECTIVES:

We sought to investigate the potential value of magnetic resonance (MR) elastography to improve the differentiation between benign and malignant tumors.

MATERIAL AND METHODS:

Measurements of 5 patients with 6 malignant lesions, 11 patients with benign lesions, and 4 patients with no lesions at all were performed at 1.5 Tesla. After breast MR imaging, MR elastography was performed as a targeted measurement. Low-frequency mechanical waves (65 Hz) were transmitted into the breast tissue using an oscillator and were displayed by means of a MR sequence within the phase of the MR image. After reconstruction, the viscoelastic information was correlated with the signal intensity and morphology data.

RESULTS:

All examinations were technically successful realized in approximately 25 minutes. Malignant tumors documented higher values of elasticity than benign corresponding with signal intensity and morphologic data.

CONCLUSION:

A good separation exists between benign and malignant lesions in elasticity, corresponding with specific signal intensity and morphologic data. Further clinical studies with a larger number of patients are needed for extended validation.

PMID:
15973132
[Indexed for MEDLINE]
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