Send to

Choose Destination
See comment in PubMed Commons below
Cancer Lett. 1992 May 30;64(1):39-42.

Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis.

Author information

Department of Medical Oncology, University of Texas, M.D. Anderson Cancer Center, Houston 77030.


Diallyl sulfide (DAS), one of a number of organosulfur compounds accounting for the flavor and smell associated with garlic, has been shown to inhibit a number of chemically induced forms of cancer. In this study, DAS was examined for its chemopreventive effects in both the initiation and post-initiation phases of nitrosomethylbenzylamine-induced esophageal carcinogenesis in the Sprague-Dawley rat. Although highly inhibitory during initiation, DAS is ineffective when given after the carcinogen. DAS, though not effective as a preventive in post-initiation, was not found to promote esophageal carcinogenesis.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center