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Emerg Infect Dis. 2005 Jun;11(6):889-94.

Fluoroquinolone-resistant Escherichia coli carriage in long-term care facility.

Author information

1
Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, USA. joel.maslow@med.va.gov

Abstract

We conducted a cross-sectional study to determine the prevalence of, and risk factors for, colonization with fluoroquinolone (FQ)-resistant Escherichia coli in residents in a long-term care facility. FQ-resistant E. coli were identified from rectal swabs for 25 (51%) of 49 participants at study entry. On multivariable analyses, prior FQ use was the only independent risk factor for FQ-resistant E. coli carriage and was consistent for FQ exposures in the previous 3, 6, 9, or 12 months. Pulsed-field gel electrophoresis of FQ-resistant E. coli identified clonal spread of 1 strain among 16 residents. Loss (6 residents) or acquisition (7 residents) of FQ-resistant E. coli was documented and was associated with de novo colonization with genetically distinct strains. Unlike the case in the hospital setting, FQ-resistant E. coli carriage in long-term care facilities is associated with clonal spread.

PMID:
15963284
PMCID:
PMC3367610
DOI:
10.3201/eid1106.041335
[Indexed for MEDLINE]
Free PMC Article

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