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J Clin Monit Comput. 2004 Dec;18(5-6):373-8.

Agreement of an inert gas rebreathing device with thermodilution and the direct oxygen Fick method in measurement of pulmonary blood flow.

Author information

1
Department of Anaesthesia, Austin Hospital, Melbourne, Australia. phil.peyton@austin.org.au

Abstract

OBJECTIVE:

Inert gas rebreathing is a well established method for the non-invasive measurement of pulmonary blood flow. We tested the agreement in measurement of pulmonary blood flow (Qt rb) by a new inert soluble gas rebreathing device, the Innocor (Innovision, Copenhagen), with bolus thermodilution (Qt td) and the direct oxygen Fick (Qt Fick) method.

METHODS:

9 patients pre- and post-cardiac surgery were recruited resulting in 20 sets of measurements overall. Arterial and mixed venous blood samples were collected simultaneously with a thermodilution measurement and rebreathing manoeuvre to measure both V*O2 and effective pulmonary capillary blood flow.

RESULTS:

Mean bias (95% confidence limits) was: Qt rb - Qt td 0.01 (+/- 0.42) L/min; Qt rb - Qt Fick + 0.34 (+/-0.59) L/min. The standard deviation of the difference between paired measurements was: Qt td - Qt rb +/- 0.89 L/min; Qt Fick - Qt rb +/- 1.26 L/min.

CONCLUSIONS:

Acceptable overall agreement between the Innocor and these reference standards was demonstrated.

PMID:
15957629
DOI:
10.1007/s10877-005-1589-6
[Indexed for MEDLINE]

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