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Neurology. 2005 Jun 14;64(11):1974-6.

Prognosis 30 years after temporal lobectomy.

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  • 1Clinical Epilepsy Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA.


To assess the long-term outcome after temporal lobectomy, the authors obtained information from 48 patients and families traced though the NIH Medical Records Department, Social Security, National Death Indices, and other sources. Preoperative evaluation, limited by current standards, was based mainly on interictal surface EEG. After a mean 29.9-year follow-up, 24 were seizure free, and 10 had died. Early seizure recurrence and invasive EEG studies predicted worse long-term outcome.

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