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Exp Parasitol. 2005 Jul;110(3):196-202. Epub 2005 Apr 8.

Genomic DNA microarrays for Entamoeba histolytica: applications for use in expression profiling and strain genotyping.

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1
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305-5124, USA.

Abstract

The parasite Entamoeba histolytica is a causative agent of dysentery and liver abscesses. Found predominantly in developing countries, this parasitic infection is responsible for significant morbidity and mortality. We have developed a genomic DNA microarray for E. histolytica. The array composed of 11,328 clones contains >2000 unique genes and was utilized for expression profiling and comparative genomic hybridizations of Entamoeba strains. We present a synopsis of our results to date and potential future applications of microarray technology for the study of Entamoeba biology.

PMID:
15955312
DOI:
10.1016/j.exppara.2005.03.006
[Indexed for MEDLINE]
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