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Biophys J. 2005 Aug;89(2):912-31. Epub 2005 Jun 10.

Cell motility as persistent random motion: theories from experiments.

Author information

1
Danish Polymer Centre, and Biosystems Department, Risø National Laboratory, Roskilde, Denmark.

Abstract

Experimental time series for trajectories of motile cells may contain so much information that a systematic analysis will yield cell-type-specific motility models. Here we demonstrate how, using human keratinocytes and fibroblasts as examples. The two resulting models reflect the cells' different roles in the organism, it seems, and show that a cell has a memory of past velocities. They also suggest how to distinguish quantitatively between various surfaces' compatibility with the two cell types.

PMID:
15951372
PMCID:
PMC1366641
DOI:
10.1529/biophysj.105.061150
[Indexed for MEDLINE]
Free PMC Article

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